2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-133108
    Azadirachtin B
    		Inhibitor 99.17%
    Azadirachtin B is an limonoid isolated from seed kernels of Azadirachta indica. Azadirachtin B increases alkaline phosphatase (ALP) activity and stimulates osteoblast differentiation. Azadirachtin B is active against the Epstein-Barr virus early antigen (EBV-EA). Azadirachtin B has insecticidal, nematocidal, anticancer, anti-inflammatory, antiviral and osteogenic properties.
    Azadirachtin B
  • HY-B1636
    Dithiazanine iodide
    		Inhibitor 99.46%
    Dithiazanine iodide is a broad-spectrum anthelmintic that induces irreversible relaxation and death of Trichuris trichiura. Dithiazanine iodide is used in research related to trichuriasis, strongyloidiasis, ascariasis, enterobiasis and hookworm infections.
    Dithiazanine iodide
  • HY-135578
    Artelinic acid
    		Inhibitor 98.14%
    Artelinic acid, a derivative of Artemisinin, is an antimalarial agent for the treatment of multidrug resistant strains of Plasmodium falciparum. Artelinic acid can be administered by various routes of administration, including intravenous, intramuscular and oral routes.
    Artelinic acid
  • HY-W133894
    Cedar oil
    		Inhibitor
    Cedar oil is an essential oil that can be extracted from numerous types of conifers. Cedar oil possesses some pesticidal properties. As a food additive and preservative, cedarwood oil is a blend of organic chemicals classified as safe compounds by the FDA.
    Cedar oil
  • HY-128421
    Tridecanedioic acid
    		Inhibitor 99.93%
    Tridecanedioic acid is an endogenous metabolite. Tridecanedioic acid is an endogenous metabolite. Tridecanedioic acid is related to the metabolic regulation of non-alcoholic fatty liver disease (NASH) and may be an important node molecule in the intestinal microbiota-host metabolism interaction network. Tridecanedioic acid is significantly accumulated in tolerant cabbage-type rapeseed varieties and has a lower content in sensitive varieties. It plays an important role in the defense response against the infection of the small cabbage moth (Plutella xylostella). Tridecanedioic acid can be used as a biomarker for plant insect resistance or a diagnostic marker for metabolic diseases.
    Tridecanedioic acid
  • HY-B1934
    Methyl stearate
    		Inhibitor 99.31%
    Methyl stearate, isolated from Rheum palmatum L. is a compopent of of soybean and rapeseed biodiesels.
    Methyl stearate
  • HY-P2274
    Argifin
    		Inhibitor 99.90%
    Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively.
    Argifin
  • HY-W010668
    Quinine sulfate hydrate
    		Inhibitor 99.97%
    Quinine sulfate hydrate (2:1:4) is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine sulfate hydrate (2:1:4) is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM.
    Quinine sulfate hydrate
  • HY-N0176R
    Dihydroartemisinin (Standard)
    		Inhibitor
    Dihydroartemisinin (Standard) is the analytical standard of Dihydroartemisinin. This product is intended for research and analytical applications. Dihydroartemisinin is a potent anti-malaria agent.
    Dihydroartemisinin (Standard)
  • HY-W749694
    Cannflavin B
    		Inhibitor 98.36%
    Cannflavin B is a flavonoid compound that can be isolated from Cannabis sativa L. Cannflavin B is inhibitors of PGE2 release (IC50: 0.7 μM), mPGES-1 (IC50: 3.7 μM), and 5-lipoxygenase. Cannflavin B has multiple activities such as anti-inflammatory, antioxidant, anti-glycation, anti-ferroptosis, anti-tumor, and anti-Leishmania (IC50: 14 μM). Cannflavin B can also inhibit the TrkB-BDNF signaling pathway.
    Cannflavin B
  • HY-106662
    Chloroquinoxaline sulfonamide
    		Inhibitor 99.06%
    Chloroquinoxaline sulfonamide (Chloroquinoxaline), a structural analogue of sulfaquinoxaline, is a topoisomerase II alpha/beta poison. Chloroquinoxaline sulfonamide is used to control coccidiosis in poultry, rabbit, sheep, and cattle. Antitumor activity.
    Chloroquinoxaline sulfonamide
  • HY-N4184
    Licoflavone B
    		Inhibitor 99.86%
    Licoflavone B is a flavonoid isolated from Glycyrrhiza inflata, inhibits S. mansoni ATPase (IC50, 23.78 µM) and ADPase (IC50, 31.50 µM) activity. Anti-schistosomiasis activity.
    Licoflavone B
  • HY-124801
    ABMA
    		Inhibitor 98.50%
    ABMA is a broad-spectrum inhibitor of intracellular toxins and pathogens. ABMA efficiently protects cells against various toxins and pathogens including viruses, intracellular bacteria and parasite. ABMA selectively acts at host cell late endosomes rather than targeting toxin or pathogen itself. ABMA has broad-spectrum anti-infection activity.
    ABMA
  • HY-Y1004
    1-Decanol
    		Inhibitor 99.79%
    1-Decanol (Decyl alcohol) is a nematicidal agent derived from Houttuynia cordata, with an LC50 of 31.5 μg/mL against potato cyst nematodes (PCN). 1-decanol directly damages nematode surface structures, induces cellular apoptosis, and disrupts the oxidative stress regulation system, while also downregulating defense-related metabolic pathways in potato, thereby promoting the reallocation of metabolic resources from defense to growth. 1-Decanol can be used for the research of potato cyst nematode infestation.
    1-Decanol
  • HY-21496
    4-(Bromomethyl)benzoic acid
    		Inhibitor 99.15%
    4-(Bromomethyl)benzoic acid (4-Carboxybenzyl bromide) is an antiparasitic agent with low activity against Leishmania amazonensis and Trypanosoma cruzi. 4-(Bromomethyl)benzoic acid has certain cytotoxicity to PBMCs, with an IC50 of 88.8 μM.
    4-(Bromomethyl)benzoic acid
  • HY-110082
    Quinine (hydrochloride)
    		Inhibitor 99.83%
    Quinine hydrochloride is an alkaloid extracted from cinchona bark and exhibits oral activity, acting as a potassium channel inhibitor. Quinine hydrochloride modulates the tolerance of red blood cells and presents dose-dependent toxicity and embryonic effects. Quinine hydrochloride is a typical hemolysin that directly lyses red blood cells, with cellular components of red blood cell membranes as its action targets. Quinine hydrochloride disrupts red blood cell membranes and induces hemolysis at high concentrations, while merely weakening the anti-hemolytic capacity of red blood cells at low concentrations. Quinine hydrochloride continuously reduces red blood cell tolerance after in vivo administration, and high doses can also alter blood cell counts. Quinine hydrochloride can be applied to researches related to red blood cell hemolysis, cancer and malaria.
    Quinine (hydrochloride)
  • HY-136450
    Triclabendazole sulfoxide
    		Inhibitor 98.34%
    Triclabendazole sulfoxide (TCBZ-SO) is an orally active ABCG2 inhibitor with antiparasitic activity. Triclabendazole sulfoxide inhibits ABCG2-mediated active efflux and ATPase activity. Triclabendazole sulfoxide increases the intracellular accumulation of Mitoxantrone (HY-13502). Triclabendazole sulfoxide reduces the apical-directed transepithelial transport of Nitrofurantoin and Danofloxacin, while increasing their basolateral-directed transepithelial transport. Triclabendazole sulfoxide elevates the plasma levels of sulfasalazine in wild-type mice. Triclabendazole sulfoxide decreases ABCG2-mediated secretion of Nitrofurantoin into milk in wild-type lactating mice. Triclabendazole sulfoxide can be used in the research of insecticidal agents and cancers such as breast cancer.
    Triclabendazole sulfoxide
  • HY-106005
    MMV390048
    		Inhibitor 98.85%
    MMV390048 is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 µM). MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. falciparum and human kinases apart from human PIP4K2C, thus alleviating potential kinase-mediated safety concerns. MMV390048 is an antimalarial agent.
    MMV390048
  • HY-B0887S
    Permethrin-d5
    		Inhibitor 99.21%
    Permethrin-d5 (NRDC-143-d5) is the deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation.
    Permethrin-d<sub>5</sub>
  • HY-N0402S
    Artemether-d3
    		Inhibitor 99.97%
    Artemether-d3 is the deuterium labeled Artemether. Artemether is an antimalarial for the treatment of resistant strains of falciparum malaria.
    Artemether-d<sub>3</sub>
Parasite Isoform Comparison

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